About the book
Transcription Factors
Normal and Malignant Development of Blood Cells
Katya Ravid and Jonathan Licht
The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification and characterization of chromosomal rearrangement in human blood leukemias.
This complete digest of current transcription factor data offers comprehensive coverage of the myriad of transcription factors in blood cell development, composed by established experts in the field. In addition to updating the reader on the connection between chromosomal translocations involving transcription factors and cellular transformation leading to leukemia, Transcription Factors also reviews such subjects as:
* Transcription factors and the megakaryocytic, myeloid, and erythroid lineages
* Leukemias due to chromosomal translocations involving gene encoding transcription factors
* Oncogenesis and hematopoiesis
* In vivo studies of transcription factors implicated in hematopoiesis
* And much more
Appealing to both the researcher and the clinician in the field of hematology, Transcription Factors is a timely presentation of cell lineage development and sheds light on the processes involved in the development of specific leukemias. Providing insight into the study of transcription factors, readers will gain an understanding of mechanisms that lead to normal lineage commitment and terminal differentiation.
Editions of Transcription Factors
- Hardcover
- ISBN 9780471350545
- EBook
- ISBN 9780471461067
- EBook
- ISBN 9780471223887
Read an Excerpt
Transcription Factors
Normal and Malignant Development of Blood Cells
Katya Ravid and Jonathan Licht
The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification and characterization of chromosomal rearrangement in human blood leukemias.
This complete digest of current transcription factor data offers comprehensive coverage of the myriad of transcription factors in blood cell development, composed by established experts in the field. In addition to updating the reader on the connection between chromosomal translocations involving transcription factors and cellular transformation leading to leukemia, Transcription Factors also reviews such subjects as:
* Transcription factors and the megakaryocytic, myeloid, and erythroid lineages
* Leukemias due to chromosomal translocations involving gene encoding transcription factors
* Oncogenesis and hematopoiesis
* In vivo studies of transcription factors implicated in hematopoiesis
* And much more
Appealing to both the researcher and the clinician in the field of hematology, Transcription Factors is a timely presentation of cell lineage development and sheds light on the processes involved in the development of specific leukemias. Providing insight into the study of transcription factors, readers will gain an understanding of mechanisms that lead to normal lineage commitment and terminal differentiation.
Frequently Asked Questions
What is Transcription Factors about?
Transcription Factors
Normal and Malignant Development of Blood Cells
Katya Ravid and Jonathan Licht
The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification and characterization of chromosomal rearrangement in human blood leukemias.
This complete digest of current transcription factor data offers comprehensive coverage of the myriad of transcription factors in blood cell development, composed by established experts in the field. In addition to updating the reader on the connection between chromosomal translocations involving transcription factors and cellular transformation leading to leukemia, Transcription Factors also reviews such subjects as:
* Transcription factors and the megakaryocytic, myeloid, and erythroid lineages
* Leukemias due to chromosomal translocations involving gene encoding transcription factors
* Oncogenesis and hematopoiesis
* In vivo studies of transcription factors implicated in hematopoiesis
* And much more
Appealing to both the researcher and the clinician in the field of hematology, Transcription Factors is a timely presentation of cell lineage development and sheds light on the processes involved in the development of specific leukemias. Providing insight into the study of transcription factors, readers will gain an understanding of mechanisms that lead to normal lineage commitment and terminal differentiation.
What core themes, tropes, or subjects are explored in Transcription Factors?
Mathematics and Science > Biology, life sciences > Molecular biology
Where can I read a sample of Transcription Factors?
You can read an official preview of the few pages here https://www.book2look.com/book/9780471350545
Who is/are the Author/s of the book Transcription Factors?
John Wiley & Sons
Who is the Publisher of the book Transcription Factors?
Wiley
What are the ISBN numbers for the physical and digital editions?
Transcription Factors is available as hardcover(ISBN 9780471350545) and ebook(ISBN 9780471461067) and ebook(ISBN 9780471223887)
Where can I buy Transcription Factors online or support local independent bookshops?
You can buy Transcription Factors from below
Where can I buy Transcription Factors?